Exosomes transmit retroelement RNAs to drive inflammation and immunosuppression in Ewing Sarcoma
V. Evdokimova, P. Ruzanov, H. Gassmann, H. H. Zaidi, V. Peltekova, L. E. Heisler, J. D. McPherson, M. Orlic-Milacic, K. Specht, K. Steiger, S. J. Schober, U. Thiel, T. D. McKee, M. Zaidi, C. M. Spring, , P. H. Sorensen
This study identifies retroelement RNAs in Ewing Sarcoma exosomes that induce inflammation and immunosuppression in recipient cells.
bioRxiv · Oct 16, 2019 · PreprintCancer Biology