Perturbation of the human gut microbiome by a non-antibiotic drug contributes to the resolution of autoimmune disease
R. R. Nayak, M. Alexander, K. Stapleton-Grey, C. Ubeda, J. U. Scher, P. J. Turnbaugh
This study shows that methotrexate, a non-antibiotic drug, alters the human gut microbiota, favoring Firmicutes over Bacteroidetes, which correlates with improved drug response in rheumatoid arthritis patients.
bioRxiv · Apr 5, 2019 · PreprintMicrobiology