A protein semisynthesis-based strategy to probe the impact of site-specific serine ADP-ribosylation on linker histone function
K. Tashiro, J. Mohapatra, C. A. Brautigam, G. Liszczak
This study develops a semisynthesis strategy to create ADP-ribosylated linker histone proteins and shows that serine ADP-ribosylation reduces chromatin compaction.
bioRxiv · Feb 17, 2022 · PreprintBiochemistry