New insights into the structure of Comirnaty Covid-19 vaccine: A theory on soft nanoparticles with mRNA-lipid supercoils stabilized by hydrogen bonds
J. Szebeni, B. Kiss, T. Bozo, K. Turjeman, Y. Levi-Kalisman, Y. Barenholz, M. Kellermayer
This paper investigates the nanoscale structure of Comirnaty mRNA-LNP vaccine using multiple imaging techniques, revealing a granular core stabilized by hydrogen bonds between mRNA and lipids.
bioRxiv · Dec 2, 2022 · PreprintImmunology