The long non-coding RNA SAMMSON is essential for uveal melanoma cell survival
S. Dewaele, L. Delhaye, B. De Paepe, E. De Bony, J. De Wilde, K. Vanderheyden, J. Anckaert, N. Yigit, E. VandenEynde, F. Nemati, D. Decaudin, A. Jochemsen, E. Leucci, J. Vandesompele, J. Van Dorpe, , P. Mestdagh
This study shows that inhibiting the lncRNA SAMMSON reduces uveal melanoma cell growth and viability by impairing mitochondrial function and protein translation.
bioRxiv · Jan 18, 2021Cancer Biology