In vivo inducible reverse genetics in patients' tumors to identify individual therapeutic targets
M. Carlet, K. Voelse, J. Vergalli, M. Becker, T. Herold, A. Arner, W.-H. Liu, V. Dill, B. Fehse, C. D. Baldus, L. Bastian, L. Lenk, D. M. Schewe, J. W. Bagnoli, P. J. Jost, , I. Jeremias
The paper develops an in vivo inducible RNAi system in patient-derived xenograft models to identify therapeutic targets in acute leukemias.
bioRxiv · May 2, 2020Cancer Biology