Platelets promote acute liver injury via extracellular vesicles-mediated Aldolase A
Ruoxue Yang, Jinghua Liu, Kai Fu, Ting Wan, Yahui Li, Can Shen, Ling Yang, Keqin Wang, Zhao Shan
This study shows platelets worsen acute liver injury by transferring aldolase A via extracellular vesicles to Kupffer cells, promoting inflammation and injury.
bioRxiv · Sep 14, 2026 · PreprintPathology