Author

Ke Fang

Chinese Academy of SciencesPrimary ORCID profile (0009-0008-0364-3294 · 2 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Ke FangiD2 papers · Guangzhou Laboratory

Biology Disciplines

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Biophysics· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:gene regulatory network inference· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:dimensionality reduction· 1

Frequent Co-Authors

Chengqi LiniD· 2 shared Haitong FangiD· 2 shared Peng XieiD· 2 shared Zhuanzhuan Che· 2 shared Zhuojuan LuoiD· 2 shared Chen Wu· 1 shared Chenghao GuoiD· 1 shared Donghan MaiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersMolecular Biology

Chengqi LinORCID

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3 papers

Recent·Most cited

Aberration-aware 3D localization microscopy via self-supervised neural-physics learning

Shuang Fu, Wei Shi, Eugene A. Katrukha, Xi Chen, Yue Fei, Ke Fang, Ruixiong Wang, Tianlun Zhang, Donghan Ma, Yiming Li

This paper introduces LUNAR, a self-supervised neural-physics learning framework for 3D localization microscopy that improves robustness to optical aberrations and high-density molecule localization.

Nature Communications · May 16, 2026Peer-reviewedBiophysics

Epigenetic delineation of the earliest cardiac lineage segregation by single-cell multi-omics

Peng Xie, Xu Jiang, Jingjing He, Qingyun Pan, Xianfa Yang, Yanying Zheng, Zhuanzhuan Che, Wenli Fan, Chen Wu, Weiheng Zheng, Shuhan Si, Kun Gao, Shiqi Zhu, Ke Fang, Haitong Fang, , Chengqi Lin

The paper uses single-cell multi-omics to study early cardiac lineage specification in mouse embryos, identifying key transcription factors and regulatory networks.

bioRxiv · May 17, 2024 · PreprintMolecular Biology

Distinct roles of the two SEC scaffold proteins, AFF1 and AFF4, in regulating RNA Pol II transcription elongation

Zhuanzhuan Che, Xiaoxu Liu, Qian Dai, Ke Fang, Chenghao Guo, Junjie Yue, Haitong Fang, Peng Xie, Zhuojuan Luo, Chengqi Lin

This study shows AFF1 and AFF4 have distinct roles in RNA Pol II transcription elongation, with AFF1 upstream and AFF4 downstream of TSS, and they function antagonistically to regulate transcription.

Journal of Molecular Cell Biology · Jul 31, 2023Peer-reviewedGenomics