Arteriolar GMP signaling revealed by FRET-based real-time measurement in vivo
Lukas Thiele, Kjestine Schmidt, Martin Thunemann, Andreas Friebe, Susanne C. Feil, Robert Feil, Cor de Wit
This study uses FRET-based imaging to measure real-time cGMP levels in arterioles of live mice, showing PDEs affect signaling duration but not amplitude, and ACh does not induce endothelial NO release.
bioRxiv · May 30, 2026 · PreprintPhysiology