Author

Kun Guo

China Pharmaceutical UniversityPrimary ORCID profile (0000-0001-6765-1957 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Kun GuoiD1 paper · University of Lincoln

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Ang LiniD· 2 shared Shiyu SuniD· 2 shared Ahmed Osman Mohamed· 1 shared Changzhen Weng· 1 shared Cheng ZhangiD· 1 shared Guan WangiD· 1 shared Jiaqing Liu· 1 shared Jiayuan Xia· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersImmunology

Ang LinORCID

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2 papers

Recent·Most cited

A Combinatorial mRNA Therapy for Treating Rheumatoid Arthritis and Osteoarthritis by Inhibiting Inflammation and Promoting Cartilage Regeneration

Guan Wang, Yixuan Guo, Kun Guo, Cheng Zhang, Ying Zhou, Jiayuan Xia, Jiaqing Liu, Jinyi Ren, Ahmed Osman Mohamed, Ke Tang, Xianmei Chen, Shiyu Sun, Yong Yang, Mingyun Shen, Yifan Huang, , Ang Lin

This paper develops a combinatorial mRNA therapy for arthritis that inhibits inflammation and promotes cartilage regeneration, showing efficacy in pre-clinical models.

bioRxiv · Dec 16, 2025 · PreprintImmunology

Leveraging mRNA platform for the development of vaccines against egg allergy

Xianyu Shao, Changzhen Weng, Lijing Liu, Kun Guo, Zhongxin Lu, Lulu Huang, 翟振华, Yixuan Guo, 狄国荣, Renmei Qiao, Jingyi Wang, Yong Yang, Shiyu Sun, Shentian Zhuang, Ang Lin

This study develops mRNA vaccines against egg allergy using a mouse model and shows they prevent anaphylaxis by inducing allergen-blocking antibodies and shifting immune responses.

Vaccines · Apr 24, 2025Peer-reviewedImmunology