L. Bruce

A clinical stage LMW-DS drug inhibits cell infection by coronaviruses and modulates reactive cytokine release from microglia

This study evaluates the LMW-DS drug ILB(R) for inhibiting coronavirus infection and modulating cytokine release from microglia, showing it blocks ACE2:spike interaction and reduces pro-inflammatory cytokines.

A clinical stage LMW-DS drug inhibits infection of human cells by Dengue, Zika and Yellow Fever viruses

This study evaluates the antiviral potential of the clinical-stage drug ILB(R) against Dengue, Zika, and Yellow Fever viruses in human cells.

SARS-CoV-2 wildlife surveillance in Ontario and Quebec, Canada

This study conducted SARS-CoV-2 surveillance in urban wildlife in Ontario and Quebec, Canada, finding no evidence of viral RNA or neutralizing antibodies in tested samples.

Extracellular Thimet Oligopeptidase is Released with Extracellular Vesicles from Human Prostate Cancer Cells

The paper shows that extracellular TOP is released with EVs from prostate cancer cells and is enzymatically active, suggesting a new role in disease progression.