Author

L. Edgington-Mitchell

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:proteomics· 2 Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

C. C. Oppy· 1 shared C. Oates· 1 shared E. L. Hartland· 1 shared E. Moisio· 1 shared H. J. Newton· 1 shared H. Jakupovic· 1 shared H. Samaranayake· 1 shared J. R. Savinainen· 1 shared

Activity by Year

2019-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMicrobiology

C. C. Oppy

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Tissue-ABPP enables high-resolution confocal fluorescence imaging of serine hydrolase activity in cryosections - Application to glioma brain unveils activity hotspots originating from tumor-associated neutrophils

N. Aaltonen, P. Singha, H. Jakupovic, T. Wirth, H. Samaranayake, S. Pasonen-Seppanen, K. Rilla, M. Varjosalo, L. Edgington-Mitchell, P. Kasperkiewicz, M. Drag, S. Kalvala, E. Moisio, J. R. Savinainen, J. T. Laitinen

The paper introduces tissue-ABPP, a method for high-resolution imaging of serine hydrolase activity in tissue sections, revealing activity hotspots in glioma tumors linked to neutrophils.

bioRxiv · Sep 26, 2019Cancer Biology

Loss of O-linked protein glycosylation in Burkholderia cenocepacia impairs biofilm formation and siderophore production via alteration of quorum sensing regulation

C. C. Oppy, L. Jebeli, M. Kuba, C. Oates, R. A. Strugnell, L. Edgington-Mitchell, M. A. Valvano, E. L. Hartland, H. J. Newton, N. E. Scott

This paper shows that loss of O-linked glycosylation in B. cenocepacia disrupts quorum sensing, leading to reduced biofilm formation and siderophore production.

bioRxiv · Sep 4, 2019 · PreprintMicrobiology