Rpl24Bst mutation suppresses colorectal cancer by promoting eEF2 phosphorylation via eEF2K
J. R. Knight, N. Vlahov, D. M. Gay, R. A. Ridgway, L. Faller, C. Proud, G. R. Mallucci, T. von der Haar, C. M. Smales, A. E. Willis, O. J. Sansom
The paper shows that Rpl24Bst mutation suppresses colorectal cancer by enhancing eEF2 phosphorylation through eEF2K, reducing protein synthesis and tumorigenesis.
bioRxiv · May 5, 2021Cancer Biology