Therapeutic assessment of targeting ASNS combined with L-Asparaginase treatment in solid tumors and investigation of resistance mechanisms
V. Apfel, D. Begue, V. Cordo, L. Holzer, L. Martinuzzi, A. Buhles, G. Kerr, I. Barbosa, U. Naumann, M. Piquet, D. Ruddy, A. Weiss, S. Ferretti, R. Almeida, D. Bonenfant, , G. G. Galli
This study assesses targeting ASNS with L-Asparaginase in solid tumors, identifies resistance mechanisms, and proposes therapeutic combinations.
bioRxiv · Sep 8, 2020Cancer Biology