Erythroid differentiation intensifies RNA mis-splicing in SF3B1-mutant myelodysplastic syndromes with ring sideroblasts
P. L. Moura, T. Mortera-Blanco, I. J. F. Hofman, G. Todisco, W. W. Kretzschmar, A.-C. Bjorklund, M. Creignou, M. Hagemann-Jensen, C. Ziegenhain, D. C. Granados, I. Barbosa, G. Walldin, M. Jansson, N. Ashley, A. J. Mead, , E. Hellstrom-Lindberg
This study investigates SF3B1-mutant myelodysplastic syndromes with ring sideroblasts by isolating RS and analyzing their development and mis-splicing during erythroid differentiation.
bioRxiv · Apr 11, 2023Cancer Biology