Accurate determination of house dust mite sensitization in asthma and allergic rhinitis through cytometric detection of Der p 1 and Der p 2 binding on Basophils (CytoBas)
L. Hsin, N. Varese, P. M. Aui, B. D. Wines, L. Mascarell, P. M. Hogarth, M. Hew, R. E. O'Hehir, M. C. van Zelm
This paper introduces the CytoBas assay, a flow cytometry method using fluorescent allergen tetramers to detect HDM sensitization in basophils, showing high sensitivity and specificity for Der p 1 and Der p 2.
bioRxiv · Aug 15, 2023Immunology