Third dose COVID-19 mRNA vaccine enhances IgG4 isotype switching and recognition of Omicron subvariants by memory B cells after mRNA but not adenovirus priming
G. E. Hartley, H. A. Fryer, P. A. Gill…·M. C. van Zelm
This study shows that a third mRNA COVID-19 vaccine dose increases IgG4+ memory B cells and Omicron subvariant recognition, but only in those primed with mRNA, not adenovirus.