Author

L. K. Fleming

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1

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Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

A. Granata· 1 shared C. Vilain· 1 shared H. S. Markus· 1 shared K. Horsburgh· 1 shared K. Patel· 1 shared M. Abramowicz· 1 shared M. Al-Thani· 1 shared M. Goodwin-Trotman· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

A. Granata

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1 paper

Recent·Most cited

A novel human iPSC model of COL4A1/A2 small vessel disease unveils a key pathogenic role of matrix metalloproteinases in extracellular matrix abnormalities

M. Al-Thani, M. Goodwin-Trotman, S. Bell, K. Patel, L. K. Fleming, C. Vilain, M. Abramowicz, S. M. Allan, T. Wang, Z. Cader, K. Horsburgh, T. Van Agtmael, S. Sinha, H. S. Markus, A. Granata

This paper develops a human iPSC model of COL4A1/A2 small vessel disease, showing that MMP inhibition rescues ECM abnormalities and mural cell defects.

bioRxiv · Feb 23, 2023 · PreprintCell Biology