Author

L. L. Buxton

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

C. D. Pernici· 1 shared C. S. Metcalf· 1 shared E. J. Dahle· 1 shared J. A. Mensah· 1 shared K. J. Johnson· 1 shared K. S. Wilcox· 1 shared L. J. Handy· 1 shared M. D. Smith· 1 shared

Activity by Year

2020-2020 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperPharmacology & Toxicology

C. D. Pernici

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1 paper

Recent·Most cited

Development of an Antiseizure Drug Screening Platform for Dravet Syndrome at the NINDS contract site for the Epilepsy Therapy Screening Program

C. D. Pernici, J. A. Mensah, E. J. Dahle, K. J. Johnson, L. J. Handy, L. L. Buxton, M. D. Smith, P. J. West, C. S. Metcalf, K. S. Wilcox

This paper evaluates a mouse model of Dravet syndrome for antiseizure drug screening, finding that it is highly refractory to common ASDs but responsive to specific treatments like clobazam and valproic acid.

bioRxiv · Dec 1, 2020Pharmacology & Toxicology