Author

L. Leconte

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Assay:proteomics· 1

Frequent Co-Authors

C. A. Valades-Cruz· 2 shared C. Wunder· 2 shared E. Dransart· 2 shared H. Leffler· 2 shared L. Johannes· 2 shared M. Shafaq-Zadah· 2 shared V. Chambon· 2 shared A. Akhil Shp· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersCell Biology

C. A. Valades-Cruz

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Author profile →

2 papers

Recent·Most cited

Growth factor-induced desialylation for the fast control of endocytosis

E. MacDonald, A. Forrester, C. A. Valades-Cruz, T. D. Madsen, J. Hetmanski, E. Dransart, Y. Ng, R. Godbole, A. Akhil Shp, L. Leconte, V. Chambon, D. Ghosh, A. Pinet, D. D. Bhatia, B. Lombard, , L. Johannes

The paper shows that growth factors induce rapid desialylation of cell surface glycoproteins, enabling reversible changes in glycan structure and function through galectin-mediated endocytosis.

Nature Cell Biology · Feb 21, 2025Peer-reviewedCell Biology

Spatial N-glycan rearrangement on α5β1 integrin nucleates galectin-3 oligomers to determine endocytic fate α

M. Shafaq-Zadah, E. Dransart, C. Wunder, V. Chambon, C. A. Valades-Cruz, L. Leconte, N. Kumar Sarangi, J. Robinson, S.-K. Bai, R. Regmi, A. Di Cicco, A. Hovasse, R. Bartels, U. Nilsson, S. Cianferani-Sanglier, , L. Johannes

The paper identifies how spatial N-glycan rearrangements on α5β1 integrin nucleate galectin-3 oligomers, determining endocytic fate and retrograde trafficking.

bioRxiv · Oct 27, 2023 · PreprintCell Biology