Author

Y. Ng

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

R. Weigert· 2 shared A. Akhil Shp· 1 shared A. Forrester· 1 shared A. Lobanov· 1 shared A. Pinet· 1 shared A. Van Dam· 1 shared B. Lombard· 1 shared B.-R. Wei· 1 shared

Activity by Year

2023-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersCancer Biology

R. Weigert

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

TRAIL-induced cytokine production via NFKB2 pathway promotes neutrophil chemotaxis and immune suppression in triple negative breast cancers

M. Kundu, Y. E. Greer, A. Lobanov, L. Ridnour, R. N. Donahue, Y. Ng, S. Ratnayake, D. Voeller, S. Weltz, Q. Chen, S. J. Lockett, M. Cam, D. Meerzaman, D. A. Wink, S. Lipkowitz

This study shows TRAIL treatment of TNBC cells activates the NFKB2 pathway, leading to cytokine production that enhances neutrophil chemotaxis and immune suppression.

bioRxiv · Jul 19, 2024 · PreprintCancer Biology

OxPhos in adipose tissue macrophages regulated by BTK enhances their M2-like phenotype and confers a systemic immunometabolic benefit in obesity

G. Purvis, M. Collino, A. Van Dam, G. Einaudi, Y. Ng, M. Shanmuganathan, S. Patel, C. Thiemermann, K. Channon, D. Greaves

This paper shows that inhibiting BTK in adipose tissue macrophages enhances OxPhos and shifts macrophages to an M2-like state, reducing inflammation and improving metabolic outcomes in obesity.

bioRxiv · Oct 9, 2023Pathology

Fusion-negative rhabdomyosarcoma orthotopic tongue xenografts for study of invasion, intravasation and metastasis in live animals

S. M. Hammoudeh, Y. Ng, B.-R. Wei, T. Madsen, R. M. Simpson, R. Weigert, P. A. Randazzo

bioRxiv · Sep 21, 2023 · PreprintCancer Biology

Growth factor-induced desialylation for the fast control of endocytosis

E. MacDonald, A. Forrester, C. A. Valades-Cruz, T. D. Madsen, J. Hetmanski, E. Dransart, Y. Ng, R. Godbole, A. Akhil Shp, L. Leconte, V. Chambon, D. Ghosh, A. Pinet, D. D. Bhatia, B. Lombard, , L. Johannes

The paper shows that growth factors induce rapid desialylation of cell surface glycoproteins, enabling reversible changes in glycan structure and function through galectin-mediated endocytosis.

bioRxiv · Sep 12, 2023Cell Biology