Pyruvate carboxylation identifies Glioblastoma Stem-like Cells opening new metabolic strategy to prevent tumor recurrence
O. Renoult, C. Gratas, N. Joalland, M. Laurent--Blond, H. Awada, M. Bourgeois, L. Oliver, S. Chiavassa, M. Croyal, F. Paris, C. Pecqueur
The paper identifies Glioblastoma Stem-like Cells (GSCs) through unique metabolic features and suggests targeting pyruvate carboxylation to prevent tumor recurrence.
bioRxiv · Jul 18, 2022Cancer Biology