Author

C. Pecqueur

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Research Focus:cancer & tumor microenvironment· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

C. Gratas· 3 shared F. Paris· 3 shared N. JOALLAND· 3 shared O. RENOULT· 3 shared H. Awada· 2 shared L. Oliver· 2 shared A. C. Parplys· 1 shared A. Clavreul· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersCancer Biology

C. Gratas

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Targeting pediatric High-Grade Gliomas with OAcGD2-CAR Vδ2 T cells

P. Thomas, M. Veerasamy, M. Devinat, E. Guiet, J. Ollier, P. Paris, N. Entz-Werle, C. Gratas, B. Clemenceau, S. Birkle, F. Paris, C. Pecqueur, S. Fougeray

This study evaluates OAcGD2-CAR T cell immunotherapy for pediatric high-grade gliomas, showing Vδ2 T cells outperform conventional β T cells in eliminating tumor cells.

bioRxiv · Nov 17, 2023 · PreprintCancer Biology

A dramatic impairment of the antitumor activity of human Vgamma9Vdelta2 T cells is induced by TGF-beta through significant phenotype, transcriptomic and metabolic changes

C. RAFIA, C. LOIZEAU, O. RENOULT, C. HARLY, C. PECQUEUR, N. JOALLAND, E. SCOTET

This study shows TGF-beta impairs Vgamma9Vdelta2 T cell antitumor activity through phenotypic, transcriptomic, and metabolic changes in vitro.

bioRxiv · Sep 22, 2022 · PreprintImmunology

Pyruvate carboxylation identifies Glioblastoma Stem-like Cells opening new metabolic strategy to prevent tumor recurrence

O. Renoult, C. Gratas, N. Joalland, M. Laurent--Blond, H. Awada, M. Bourgeois, L. Oliver, S. Chiavassa, M. Croyal, F. Paris, C. Pecqueur

The paper identifies Glioblastoma Stem-like Cells (GSCs) through unique metabolic features and suggests targeting pyruvate carboxylation to prevent tumor recurrence.

bioRxiv · Jul 18, 2022Cancer Biology

Mechanistic insights of radiation-induced endothelial senescence impelling glioblastoma genomic instability at relapse

C. Degorre, O. Renoult, A. C. Parplys, H. Awada, A. Clavreul, M. Pietri, L. Oliver, N. Joalland, M. Ricoul, C. Gratas, F. Vallette, K. Borgmann, L. Sabatier, C. Pecqueur, F. Paris

This study identifies radiation-induced endothelial senescence as a driver of genomic instability and aggressiveness in relapsing glioblastoma through CXCL5/CXCL8-CXCR2 signaling.

bioRxiv · Dec 13, 2021 · PreprintCancer Biology