Enhanced donor antigen presentation by B-cells predicts acute cellular rejection and late outcomes after transplantation.
C. Ashokkumar, M. Ningappa, V. Raghu, G. Mazariegos, B. W. Higgs, P. Morgan, L. Remaley, T. Fazzolare, P. Holzer, K. Trostle, Q. Xu, A. Zeevi, J. Squires, K. Soltys, S. Horslen, , R. Sindhi
The paper shows that a higher antigen presenting index (API) in B-cells predicts acute rejection and poor long-term outcomes after liver or intestine transplantation.
bioRxiv · Oct 17, 2022Immunology