Author

P. Holzer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 2 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

, A. Ganoza· 1 shared A. Hofmann· 1 shared A. Khanna· 1 shared A. Vulpetti· 1 shared A. Zeevi· 1 shared B. Bauer-Probst· 1 shared B. Chung· 1 shared B. Pinch· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperImmunology

, A. Ganoza

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Reinstating targeted protein degradation with DCAF1 PROTACs in CRBN PROTAC resistant settings

M. Schroeder, M. Renatus, X. Liang, F. Meili, S. Ferrand, F. Gauter, X. Li, F. Sigoillot, S. Gleim, M.-T. Stachyra, J. Thomas, M. Schirle, T. Zoller, D. Begue, P. Lefeuvre, , C. R. Thoma

This study develops DCAF1-based PROTACs to overcome CRBN resistance in targeted protein degradation, demonstrating effective degradation of BTK in CRBN-resistant cells.

bioRxiv · Apr 9, 2023 · PreprintBiochemistry

Enhanced donor antigen presentation by B-cells predicts acute cellular rejection and late outcomes after transplantation.

C. Ashokkumar, M. Ningappa, V. Raghu, G. Mazariegos, B. W. Higgs, P. Morgan, L. Remaley, T. Fazzolare, P. Holzer, K. Trostle, Q. Xu, A. Zeevi, J. Squires, K. Soltys, S. Horslen, , R. Sindhi

The paper shows that a higher antigen presenting index (API) in B-cells predicts acute rejection and poor long-term outcomes after liver or intestine transplantation.

bioRxiv · Oct 17, 2022Immunology