Modulation of Transient receptor potential melastatin 3 by protons through its intracellular binding sites
M. Z. Hossain Saad, L. Xiang, Y.-S. Liao, L. Reznikov, J. Du
This study identifies three intracellular residues that modulate TRPM3 channel activity through pH sensitivity, revealing their role in proton-induced inhibition and channel gating.
bioRxiv · Oct 8, 2020 · PreprintPharmacology & Toxicology