Author

L. Talbert

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Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Kang· 1 shared B. Ford· 1 shared C. Augello· 1 shared D. Riggs· 1 shared E. Coburn· 1 shared J. Noll· 1 shared J. Tang· 1 shared R. Julian· 1 shared

Activity by Year

2019-2019 · peak 1/yr

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9 top collaborators · 36 mutual co-author links

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1 shared paperBiochemistry

A. Kang

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1 paper

Recent·Most cited

Spontaneous isomerization of long-lived proteins provides a molecular mechanism for the lysosomal failure observed in Alzheimer’s disease

T. Lambeth, D. Riggs, L. Talbert, J. Tang, E. Coburn, A. Kang, J. Noll, C. Augello, B. Ford, R. Julian

This paper shows that isomerization of long-lived proteins in Alzheimer’s disease prevents lysosomal digestion, leading to lysosomal failure and linking AD to lysosomal storage disorders.

bioRxiv · Apr 18, 2019Biochemistry