Author

Lars Olson

Karolinska Institutet

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Genetics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Assay:imaging· 1 Assay:proteomics· 1

Frequent Co-Authors

Giuseppe CoppotelliiD· 2 shared Jaime M. RossiD· 2 shared Angela Kim· 1 shared Brian Gallagher· 1 shared Carole Bassa· 1 shared Christopher Hemme· 1 shared David A. SinclairiD· 1 shared Emmanuel SotirakisiD· 1 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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2 shared papersGenetics

Giuseppe CoppotelliORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A novel inducible mtDNA mutator mouse model to study mitochondrial dysfunction with temporal and spatial control

Hannah Tobias-Wallingford, Sydney Bartman, Lauren Gaspar, Brian Gallagher, Carole Bassa, Emmanuel Sotirakis, Vincent Dubus, Christopher Hemme, Lars Olson, Giuseppe Coppotelli, Jaime M. Ross

This paper develops an inducible mtDNA mutator mouse model to study mitochondrial dysfunction with spatial and temporal control, showing it recapitulates the original model's phenotype.

Innovation in Aging · Dec 1, 2025Peer-reviewedGenetics

Mitochondrial Dysfunction Induces Hepatic Lipid Accumulation and Inflammatory Responses in mtDNA Mutator Mice

Jaime M. Ross, Angela Kim, Kayla Berthod, Rui Mamede Branca, Maria Olin, Israel Pichardo‐Casas, Janne Lehtiö, Ingemar Björkhem, David A. Sinclair, Lars Olson, Giuseppe Coppotelli

This study shows mitochondrial dysfunction causes liver lipid accumulation and inflammation in mtDNA mutator mice without obesity or insulin resistance.

bioRxiv · Apr 25, 2025 · PreprintCell Biology

Spatio-temporal brain invasion pattern of Streptococcus pneumoniae and dynamic changes of the cellular environment in meningitis pathogenesis.

Kristine Farmen, Miguel Tofiño-Vian, Katrin Wellfelt, Lars Olson, Federico Iovino

This study investigates the spatio-temporal invasion pattern of Streptococcus pneumoniae in the brain during meningitis and its impact on cellular environments.

bioRxiv · Oct 30, 2023 · PreprintNeuroscience