Author

Laurel Stine

University of Massachusetts Chan Medical School

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Fiachra HumphriesiD· 2 shared Liraz Shmuel-GaliaiD· 2 shared Sara E. CahilliD· 2 shared Abigail Sondrini· 1 shared Evelyn A. Kurt‐JonesiD· 1 shared G. Scott PesiridisiD· 1 shared John BertiniD· 1 shared Joshi M. RamanjuluiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersImmunology

Fiachra HumphriesORCID

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2 papers

Recent·Most cited

Non-canonical TLR signaling restricts cytosolic LPS detection.

Shriram Ramani, Sara E. Cahill, Matthew Finnegan, Laurel Stine, Abigail Sondrini, Kiera Clayton, Liraz Shmuel-Galia, Fiachra Humphries

This study identifies MARCO as a decoy LPS sensor regulated by non-canonical TLR signaling, which restricts inflammasome activation and prevents excessive inflammation.

The Journal of Immunology · Jul 28, 2026Peer-reviewedImmunology

Alternative cGAS signaling promotes Herpes simplex encephalitis

Liraz Shmuel-Galia, Zhaozhao Jiang, Laurel Stine, Sara E. Cahill, Sze‐Ling Ng, Ruth Wilson, Richard K. Kandasamy, Evelyn A. Kurt‐Jones, Joshi M. Ramanjulu, John Bertin, Viera Kasparcova, G. Scott Pesiridis, Katherine A. Fitzgerald, Fiachra Humphries

This study identifies an alternative cGAS signaling pathway independent of cGAMP that promotes neutrophil recruitment and viral dissemination in herpes simplex encephalitis.

Proceedings of the National Academy of Sciences · May 27, 2025Peer-reviewedImmunology