Leonard Kuan

Stimulus novelty uncovers coding diversity in survey of visual cortex

The paper identifies diverse functional neuron types in the visual cortex that process novel and familiar stimuli in mice.

A whole-brain monosynaptic input connectome to neuron classes in mouse visual cortex

The paper maps brain-wide monosynaptic inputs to specific neuron classes in mouse visual cortex using an improved rabies virus tracing strategy and identifies connectivity patterns within and between visual areas.

Regional, layer, and cell-class specific connectivity of the mouse default mode network

This study identifies the anatomical composition and connectivity patterns of the mouse default mode network at the regional, layer, and cell-class levels.

A large-scale, standardized physiological survey reveals higher order coding throughout the mouse visual cortex

The paper presents a large-scale dataset of neural activity in the mouse visual cortex and shows that responses to different stimuli are largely independent, suggesting multi-layer hierarchical computation.

The organization of intracortical connections by layer and cell class in the mouse brain

The paper expands the Allen Mouse Brain Connectivity Atlas by analyzing intracortical connections at the layer and cell class level, revealing modular organization and distinct projection patterns.

Whole brain imaging reveals distinct spatial patterns of amyloid beta deposition in three mouse models of Alzheimer’s disease

The paper uses whole brain imaging to compare amyloid beta deposition patterns in three Alzheimer's disease mouse models, revealing distinct spatial distributions across brain regions.