Joseph E. Knox

The paper uses whole-brain imaging to show that tau pathology in mice propagates retrogradely through brain networks.

The paper quantifies whole-brain XCI at single-cell resolution and finds a 60:40 paternal-to-maternal inactivation ratio that reduces disease penetrance in Fragile-X models.

This study identifies the anatomical composition and connectivity patterns of the mouse default mode network at the regional, layer, and cell-class levels.

The paper expands the Allen Mouse Brain Connectivity Atlas by analyzing intracortical connections at the layer and cell class level, revealing modular organization and distinct projection patterns.

The paper uses whole brain imaging to compare amyloid beta deposition patterns in three Alzheimer's disease mouse models, revealing distinct spatial distributions across brain regions.

The paper constructs a high-resolution voxel-scale model of the mouse connectome using anterograde tracing data, outperforming previous regional models.