Author

Lili Chen

Huazhong University of Science and TechnologyPrimary ORCID profile (0000-0003-0026-4877 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Lili CheniD1 paper

Biology Disciplines

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Neuroscience· 3 Cancer Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:C. elegans· 3 Assay:electronic health records· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Shangbang GaoiD· 3 shared Mei ZheniD· 2 shared Wesley HungiD· 2 shared Zhongpu Yue· 2 shared Ailing Zou· 1 shared Bin YuiD· 1 shared Caiming WuiD· 1 shared changbing zhangiD· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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3 shared papersNeuroscience

Shangbang GaoORCID

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Author profile →

5 papers

Recent·Most cited

FASN Inactivation-induced Progranulin (GRN) Expression Promotes Lysosome-dependent Cell Death to Suppress Leukemogenesis

Meng Su, Qinglin Li, Zhiyi Lv, Xinshu Xie, Yating Lu, Yaohui He, Hanqi Liu, Hui Cao, Jie Ouyang, Qiao Zhang, Xuezhen Ma, Yexin Yang, Ailing Zou, Kang Liu (423471), Shuqian Xu, , Yang Mei

This study shows that inhibiting FASN leads to lysosome-dependent cell death via GRN expression, suppressing leukemogenesis in myeloid leukemia.

Cell Reports · Mar 1, 2026Peer-reviewedCancer Biology

A high-continuity and annotated reference genome of allotetraploid Siberian wildrye (Elymus sibiricus L., Poaceae: Triticeae)

Jiajun Yan, Xinrui Li, Lili Wang, Daxu Li, Changmian Ji, Zujun Yang, Lili Chen, changbing zhang, Minghong You, Lijun Yan, Wenlong Gou, Xiong Lei, Xiaofei Ji, Yingzhu Li, Qi Wu, , Shiqie Bai

This study presents a high-quality reference genome for the allotetraploid Siberian wildrye, revealing retrotransposon bursts, chromosomal translocations, and population structure, supporting the QTP as its origin.

bioRxiv · Apr 17, 2024 · PreprintGenomics

A Leak K+ Channel TWK-40 Regulates Rhythmic Motor Program in C. elegans

Zhongpu Yue, Yi Li, Bin Yu, Yueqing Xu, Lili Chen, Jyothsna Chitturi, Jun Meng, Wesley Hung, Yuhang Tian, Sonia El Mouridi, Cuntai Zhang, Thomas Boulin, Mei Zhen, Shangbang Gao

This study identifies TWK-40, a K2P channel, as essential for regulating rhythmic motor activity in C. elegans by modulating DVB neuron function and Ca2+ oscillations.

bioRxiv · Apr 9, 2022 · PreprintNeuroscience

Escape Steering by Cholecystokinin Peptidergic Signaling

Lili Chen, Yuting Liu, Pan Su, Wesley Hung, Haiwen Li, Ya Wang, Zhongpu Yue, Ming-Hai Ge, Zheng‐Xing Wu, Yan Zhang, Peng Fei, Liming Chen, Louis Tao, Heng Mao, Mei Zhen, Shangbang Gao

The paper identifies cholecystokinin signaling as essential for robust escape steering in C. elegans by modulating motor neuron activity during escape responses.

Cell Reports · Feb 1, 2022Peer-reviewedNeuroscience

Male pheromones modulate synaptic transmission at the C. elegans neuromuscular junction in a sexually dimorphic manner

Kang‐Ying Qian, Wan-Xin Zeng, Yue Hao, Xian-Ting Zeng, Haowen Liu, Lei Li, Lili Chen, Fu-min Tian, Cindy Y. Chang, Qi Hall, Chun-Xue Song, Shangbang Gao, Zhitao Hu, Joshua M. Kaplan, Qian Li, Xia-Jing Tong

This study shows that male pheromones in C. elegans enhance hermaphrodite cholinergic synaptic transmission at the neuromuscular junction, affecting locomotion and mating efficiency.

eLife · Mar 31, 2021Peer-reviewedNeuroscience