Chimeric archaeal BHB-human pre-tRNA scaffold HARBOR system enables versatile production of functional circular RNA modalities
Shi-Meng Cao, Xin Feng, J.Tian-Chang Zhang, Hao Wu, Xiao Wang, Keqiong Ye, Ling-Ling Chen
The paper introduces the HARBOR system for producing functional circular RNAs with high efficiency and versatility in both cells and vivo.
bioRxiv · Oct 13, 2026 · PreprintMolecular Biology