Mechano-Initiated PIEZO1-VEGFR2 Interaction Governs CD34+ Cell Differentiation and Repair in Arteriovenous Fistula
Pengwei Zhu, Yakui Wu, Linlin Lu, Tao Huang, Ruihan Chen, Yanhua Hu, Liujun Jiang, Xuliang Wang, Qingbo Xu, Jiang‐Yun Luo, Xiaosheng Hu
This study identifies PIEZO1-VEGFR2 interaction as a mechanotransduction axis regulating CD34+ cell differentiation and endothelial repair in arteriovenous fistulas through the AKT-FoxO1 pathway.
bioRxiv · Jun 10, 2026 · PreprintCell Biology