Systems BiologybioRxivPreprint
A systemic circadian nicotinic acid riboside (NaR) signal engages the unfolded protein response and adipogenesis via the prefoldin complex
Ivan Vlassakev, Christina Savva, Liying Zhou…·Paul Petrus
This paper identifies NaR as a liver clock-controlled metabolite that links circadian rhythms to adipogenesis via the prefoldin complex and UPR signaling.
DOI 10.64898/2026.03.04.709493