Precise Control of Switchable Chimeric Antigen Receptor T Cells Allows Enhanced Safety and Less T Cell Exhaustion
Zihan Anna Zhang, Logan Herring, Thuzar Hla Shwe, Yue Hu, Xiaotong Song, Wenyue Cao, Wenshe Ray Liu
This study develops a switchable CAR-T cell system that allows precise control of CAR activity, reducing toxicity and exhaustion while maintaining therapeutic efficacy.
Journal of Translational Medicine · Jun 17, 2026Peer-reviewedCancer Biology