Wenshe Ray Liu

This paper introduces UbCMK, a probe that selectively profiles E2 ubiquitin conjugating enzymes and DUBs, revealing their activity under various stress conditions.

This study develops a switchable CAR-T cell system that allows precise control of CAR activity, reducing toxicity and exhaustion while maintaining therapeutic efficacy.

This paper identifies the ENL-USP7 complex as a host factor that stabilizes BRD4 to maintain HIV-1 latency and shows that disrupting this complex reactivates latent HIV.

This paper develops first-in-class PROTAC degraders of SARS-CoV-2 main protease, showing they reduce MPro levels and exhibit anti-SARS-CoV-2 activity.