Author

Lorenz Over

Hertie Institute for Clinical Brain Research

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Elisabeth M.M. BrandiD· 1 shared Hang LyuiD· 1 shared Hubert KalbacheriD· 1 shared Peter MülleriD· 1 shared Remy Lambert· 1 shared Stefano Iavarone· 1 shared Ulrike B. S. HedrichiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperNeuroscience

Elisabeth M.M. BrandORCID

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1 paper

Recent·Most cited

Scorpion toxin peptide BMK86-P1 achieves mutation-reversible inhibition of KCNA2 at the cost of reduced efficacy in heteromers and murine neurons

Elisabeth M.M. Brand, Lorenz Over, Hubert Kalbacher, Remy Lambert, Stefano Iavarone, Hang Lyu, Ulrike B. S. Hedrich, Peter Müller

The paper demonstrates that the scorpion toxin BMK86-P1 selectively inhibits KV1.2 homomers but not heteromers, with a mutation reducing its efficacy and altering channel activation.

bioRxiv · Sep 3, 2026 · PreprintNeuroscience