Author

Lu Cai

University of LouisvillePrimary ORCID profile (0000-0003-3048-1135 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Lu CaiiD1 paper · University of the Pacific

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:clustering· 1 Approach:contrastive learning· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

Ahmed Abdelbsset-Ismail· 1 shared Alex P. CarlliD· 1 shared Changping LiiD· 1 shared Charles C. DaiiD· 1 shared Debodipta DasiD· 1 shared Eric Jiang· 1 shared Francis E. SharkeyiD· 1 shared Francisco G. CigarroaiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBioinformatics

Ahmed Abdelbsset-Ismail

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2 papers

Recent·Most cited

Distinct and shared synergistic effects of high-fat and high-iron diets on liver tumorigenesis and transcriptomic remodeling in mice

Debodipta Das, Hakim Bouamar, Xiaoli Sun, Jason Xu, Lu Cai, Yidong Chen, Francis E. Sharkey, Sukeshi Patel Arora, Francisco G. Cigarroa, Lu‐Zhe Sun

This study examines how high-fat and high-iron diets affect liver tumorigenesis and transcriptomic changes in mice, finding shared and distinct molecular effects.

bioRxiv · May 27, 2026 · PreprintCancer Biology

TOGGLE delineates fate and function within individual cell types via single cell transcriptomics

Junpeng Chen, Tianda Sun, Tian Song, Zhouweiyu Chen, Haowei Xu, Zixuan Guo, Eric Jiang, Yibing Nong, Tao Yuan, Charles C. Dai, Yexing Yan, Jinwen Ge, Haihui Wu, Tong Yang, Shanshan Wang, , Alex P. Carll

TOGGLE identifies functional heterogeneity within cell types using single-cell transcriptomics, revealing distinct states like ferroptosis and apoptosis in ischemic stroke and uncovering epigenetic memory in neural stem cells.

bioRxiv · Jan 1, 2025 · PreprintBioinformatics