Author

Lucas McClain

University of Cincinnati

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Yu LuoiD· 2 shared Александр ТарановiD· 2 shared Aditi ParanjpeiD· 1 shared Alicia BedollaiD· 1 shared Anastasia AlkhimovitchiD· 1 shared Cameron SadeghiD· 1 shared Elliot Wegman· 1 shared Eric Kniffen· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersNeuroscience

Yu LuoORCID

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2 papers

Recent·Most cited

Ablation of the choroid plexus attenuates hydrocephalus induced parenchymal edema but moderately reduces postnatal hippocampal neurogenesis

Александр Таранов, Florian Mayrhofer, Sage Hamm, Eric Kniffen, Joshua Peter, Felissa Wallace, Olivia Lullmann, Lucas McClain, Olga V. Chechneva, Cameron Sadegh, Yu Luo

This study investigates the effects of choroid plexus ablation on hydrocephalus and neurogenesis, finding that it reduces parenchymal edema but only moderately affects hippocampal neurogenesis.

bioRxiv · Jul 30, 2026 · PreprintNeuroscience

Microglia-derived TGF-β1 ligand maintains microglia homeostasis via autocrine mechanism and is critical for normal cognitive function in adult mouse brain

Alicia Bedolla, Elliot Wegman, Max Weed, Messiyah K. Stevens, Kierra Ware, Aditi Paranjpe, Anastasia Alkhimovitch, Igal Ifergan, Александр Таранов, Joshua D. Peter, Rosa Maria Salazar Gonzalez, J. Elliott Robinson, Lucas McClain, Krishna M. Roskin, Nigel H. Greig, Yu Luo

This study identifies microglia as the primary source of TGF-β1 ligand in the adult mouse brain, showing its role in maintaining microglial homeostasis and cognitive function through an autocrine mechanism.

Nature Communications · Jun 21, 2024Peer-reviewedNeuroscience