Psychedelic Hormesis: LSD Activates Adaptive Stress Transcriptional Programs in the Prefrontal Cortex
Aurora Savino, Carla Liaci, Giorgio Roberto Merlo, Lucia Prandi, Lidia Avalle, Valeria Poli
This study shows LSD induces adaptive stress transcriptional programs in the prefrontal cortex of mice, aligning with hormetic adaptation rather than chronic stress.
bioRxiv · Sep 18, 2026 · PreprintMolecular Biology