Author

Luise Graichen

German Primate Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 6 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Organism:human· 4 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Markus HoffmanniD· 7 shared Hans‐Martin JäckiD· 6 shared Sebastian R. SchulziD· 6 shared Stefan PöhlmanniD· 6 shared Amy Madeleine Kempf· 5 shared Georg M. N. BehrensiD· 5 shared Martin Sebastian WinkleriD· 5 shared Nadine KrügeriD· 5 shared

Activity by Year

2021-2026 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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7 shared papersMolecular Biology

Markus HoffmannORCID

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Epidemiology and virological characteristics of the emerging SARS-CoV-2 variant PJ.2.1

Markus Hoffmann, Lu Zhang, Nianzhen Chen, Nicole de Moor, Inga Nehlmeier, Luise Graichen, Anna-Sophie Moldenhauer, Alexandra Dopfer‐Jablonka, Christine Happle, Georg M. N. Behrens, Stefan Poehlmann

The paper characterizes the epidemiology and virology of the SARS-CoV-2 variant PJ.2.1, finding it spreads mainly in older adults and shows increased ACE2 binding but not greater antibody evasion.

bioRxiv · Oct 8, 2026 · PreprintMicrobiology

Virological traits of the SARS-CoV-2 BA.2.87.1 lineage

Lu Zhang, Alexandra Dopfer‐Jablonka, Inga Nehlmeier, Amy Madeleine Kempf, Luise Graichen, Noemí Calderón Hampel, Anne Cossmann, Metodi V. Stankov, Gema Morillas Ramos, Sebastian R. Schulz, Hans‐Martin Jäck, Georg M. N. Behrens, Stefan Pöhlmann, Markus Hoffmann

This study investigates the virological traits of the SARS-CoV-2 BA.2.87.1 lineage, finding it efficiently enters human cells but is more sensitive to antibody neutralization than JN.1.

Vaccines · May 1, 2024Peer-reviewedMolecular Biology

ACE2-independent sarbecovirus cell entry is supported by TMPRSS2-related enzymes and reduces sensitivity to antibody-mediated neutralization

Lu Zhang, Hsiu-Hsin Cheng, Nadine Krüger, Bojan F. Hörnich, Luise Graichen, Alexander S. Hahn, Sebastian R. Schulz, Hans‐Martin Jäck, Metodi V. Stankov, Georg M. N. Behrens, Marcel A. Müller, Christian Drosten, Onnen Moerer, Martin Sebastian Winkler, Zhaohui Qian, , Markus Hoffmann

This study identifies an ACE2-independent pathway for sarbecovirus entry in human cells, mediated by TMPRSS2-related proteases and linked to reduced antibody neutralization.

bioRxiv · Apr 18, 2024 · PreprintMolecular Biology

SARS-CoV-2 variant B.1.617 is resistant to Bamlanivimab and evades antibodies induced by infection and vaccination

Markus Hoffmann, Heike Hofmann-Winkler, Nadine Krüger, Amy Madeleine Kempf, Inga Nehlmeier, Luise Graichen, Prerna Arora, Anzhalika Sidarovich, Anna-Sophie Moldenhauer, Martin Sebastian Winkler, Sebastian R. Schulz, Hans‐Martin Jäck, Metodi V. Stankov, Georg M. N. Behrens, Stefan Pöhlmann

Cell Reports · Jun 29, 2021Peer-reviewedMolecular Biology

Increased lung cell entry of B.1.617.2 and evasion of antibodies induced by infection and BNT162b2 vaccination

Prerna Arora, Amy Madeleine Kempf, Inga Nehlmeier, Anzhalika Sidarovich, Nadine Krüger, Luise Graichen, Anna-Sophie Moldenhauer, Martin Sebastian Winkler, Sebastian R. Schulz, Hans‐Martin Jäck, Metodi V. Stankov, Georg M. N. Behrens, Stefan Pöhlmann, Markus Hoffmann

This study shows that the B.1.617.2 variant of SARS-CoV-2 evades antibodies from infection and vaccination, increases lung cell entry, and enhances cell fusion.

bioRxiv · Jun 23, 2021 · PreprintMolecular Biology

SARS-CoV-2 mutations acquired in mink reduce antibody-mediated neutralization

Markus Hoffmann, Lu Zhang, Nadine Krüger, Luise Graichen, Hannah Kleine‐Weber, Heike Hofmann-Winkler, Amy Madeleine Kempf, Stefan Nessler, Joachim Riggert, Martin Sebastian Winkler, Sebastian R. Schulz, Hans‐Martin Jäck, Stefan Pöhlmann

The paper shows that SARS-CoV-2 mutations from mink reduce antibody neutralization, suggesting potential risks for human infections.

Cell Reports · Apr 1, 2021Peer-reviewedMolecular Biology

SARS-CoV-2 variants B.1.351 and B.1.1.248: Escape from therapeutic antibodies and antibodies induced by infection and vaccination

Markus Hoffmann, Prerna Arora, Rüdiger M. Groß, Alina Seidel, Bojan F. Hörnich, Alexander S. Hahn, Nadine Krüger, Luise Graichen, Heike Hofmann-Winkler, Amy Madeleine Kempf, Martin Sebastian Winkler, Sebastian R. Schulz, Hans‐Martin Jäck, Bernd Jahrsdörfer, Hubert Schrezenmeier, , Stefan Pöhlmann

Cell · Mar 20, 2021Peer-reviewedMolecular Biology