Structural basis for TORC2 activation
Luoming Zou, Maria G. Tettamanti, Caroline Gabus, Ariane Bergmann, Robbie Loewith, Lucas Tafur
This study determines the cryo-EM structure of yeast TORC2, revealing how phosphoinositides activate it through structural rearrangements involving regulatory subunits.
Molecular Cell · Apr 1, 2026Peer-reviewedBiochemistry