Lucas Tafur

This study determines the cryo-EM structure of yeast TORC2, revealing how phosphoinositides activate it through structural rearrangements involving regulatory subunits.

This study determines the cryo-EM structure of the SEAC-EGOC supercomplex in yeast and shows its role in amino acid signaling to TORC1, revealing how SEACIT and SEACAT regulate this process.

The paper presents cryo-EM structures of yeast Pol I elongation complexes bound to GMPCPP, revealing structural rearrangements involving TFIIE/TFIIF-like and TFIIS-like subunits.