Lipid accumulation promotes scission of caveolae
M. Hubert, E. Larsson, N. V. G. Vegesna, M. Ahnlund, A. I. Johansson, L. W. K. Moodie, R. Lundmark
The paper shows that cholesterol and glycosphingolipids accumulate in caveolae, reducing their neck diameter and promoting scission from the cell surface, counteracted by EHD2.
bioRxiv · Jan 22, 2020Biochemistry