Role of nanoscale antigen organization on B-cell activation probed using DNA origami
R. Veneziano, T. Moyer, M. B. Stone, T. R. Shepherd, W. R. Schief, D. J. Irvine, M. Bathe
This study uses DNA origami to investigate how antigen organization affects B-cell activation, finding that optimal spacing and valency enhance signaling.
bioRxiv · Feb 16, 2020Immunology