Author

M. Bonus

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Physiology· 1

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

A. Bastianelli· 1 shared A. Behrendt· 1 shared A. Stalke· 1 shared C. Droege· 1 shared E.-D. Pfister· 1 shared H. Gohlke· 1 shared J. Stindt· 1 shared K. Grau· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperPhysiology

A. Bastianelli

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1 paper

Recent·Most cited

Impaired transitioning of the FXR ligand binding domain to an active state underlies an FXR-associated PFIC phenotype

A. Behrendt, A. Bastianelli, J. Stindt, E.-D. Pfister, M. Sgodda, T. Cantz, S. Hook, K. Grau, S. Brands, C. Droege, A. Stalke, M. Bonus, S. Franke, U. Baumann, V. Keitel, H. Gohlke

This study identifies a missense variant in FXR that impairs its conformational transition to an active state, leading to reduced BSEP expression and a PFIC phenotype.

bioRxiv · Feb 8, 2024 · PreprintPhysiology