Cleaving DNA with DNA: cooperative tuning of structure and reactivity driven by copper ions
S. C. Dantu, M. Khalil, M. Bria, C. Saint-Pierre, D. Gasparutto, G. Sicoli
The paper analyzes a copper-dependent DNAzyme using molecular dynamics and EPR/ESR spectroscopy to reveal structural and mechanistic details of its self-cleavage reaction.
bioRxiv · Jun 6, 2023Biophysics