Author

M. C. Cobanoglu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:drug response / drug discovery· 2 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

V. Siruvallur Murali· 2 shared A. Wise· 1 shared B.-J. Chang· 1 shared D. A. Cobanoglu· 1 shared D. Agac Cobanoglu· 1 shared D. Farrar· 1 shared E. S. Welf· 1 shared E. Welf· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersCancer Biology

V. Siruvallur Murali

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Adrenergic signaling controls early transcriptional programs during CD8+ T cell responses to viral infection

L. Estrada, D. A. Cobanoglu, A. Wise, R. Maples, M. C. Cobanoglu, D. Farrar

This study shows that ADRB2 signaling regulates key transcriptional pathways in CD8+ T cells during viral infection, affecting their expansion, cytokine production, and memory development.

bioRxiv · Oct 20, 2021Immunology

Cancer drug discovery as a low rank tensor completion problem

V. Siruvallur Murali, D. Agac Cobanoglu, M. Hsieh, M. Zinn, V. S. Malladi, J. Gesell, N. S. Williams, E. S. Welf, G. V. Raj, M. C. Cobanoglu

This paper frames cancer drug discovery as a low rank tensor completion problem and identifies novel drug candidates through computational methods and experimental validation.

bioRxiv · Mar 8, 2021 · PreprintCancer Biology

An image-based assay to quantify changes in proliferation and viability upon drug treatment in 3D microenvironments

V. Siruvallur Murali, B.-J. Chang, R. Fiolka, G. Danuser, M. C. Cobanoglu, E. Welf

This paper introduces an image-based assay to measure drug effects on cell proliferation and viability in 3D microenvironments, showing 3D single cells are as effective as spheroids for drug screening.

bioRxiv · Feb 27, 2019Cancer Biology