Author

M. Champion

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

K. R. Nicholson· 2 shared P. A. Champion· 2 shared R. M. Cronin· 2 shared A. R. Menon· 1 shared B. S. Jones· 1 shared D. D. Hu· 1 shared D. M. Tobin· 1 shared M. K. Jennisch· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersMicrobiology

K. R. Nicholson

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

The antagonistic transcription factors, EspM and EspN, regulate the ESX-1 secretion system in M. marinum

K. R. Nicholson, R. M. Cronin, R. J. Prest, A. R. Menon, Y. Yang, M. K. Jennisch, M. Champion, D. M. Tobin, P. A. Champion

This study identifies EspN as a critical transcription factor regulating the ESX-1 system in M. marinum, which is essential for macrophage infection and disease burden, but its activity is masked by EspM under laboratory conditions.

bioRxiv · Jan 9, 2024Microbiology

The loss of the PDIM/PGL virulence lipids causes differential secretion of ESX-1 substrates in Mycobacterium marinum

B. S. Jones, D. D. Hu, K. R. Nicholson, R. M. Cronin, M. Champion, P. A. Champion

This study shows that loss of PDIM and PGL lipids in M. marinum reduces specific ESX-1 substrate secretion, impacting pathogenesis.

bioRxiv · Jan 9, 2024 · PreprintMicrobiology